High-standard, high-quality raw material system: The proprietary manufacturing foundation of CrystoGen™ microcrystal spheres.

In pet intestinal nutrition, what truly determines stability is not merely whether the raw materials themselves “have functionality,” but rather whether there is an understanding of and control over the raw material production process.

Since its founding, NEWGEN has consistently adhered to the principle of “research-driven and industry-rooted,” and has been committed to independent R&D and building its own production lines.

Currently, our product line covers enzymes, probiotics, functional polysaccharides, and a variety of active ingredients. Based on our proprietary production system, we are involved from the very beginning—participating in the design, manufacturing, and optimization of raw materials—ensuring that the raw materials themselves are tailored for subsequent structured delivery and formulation applications.

Manufacturing capability determines the system's upper limit.

 

The CrystoGen™ raw material system is built on a foundation of in-house production, with its core advantage lying in the controllability of key processes. This controllability is reflected in the fermentation process, the enzyme preparation pathway, and the simultaneous development of functional active ingredients—whose primary goal is to provide a stable basis for subsequent structured applications.

During the production stage, raw materials are already factored into considerations regarding the stability, drug-loading capacity, and subsequent structural compatibility of CrystoGen™ pet microcrystals, making them better suited for multi-layer encapsulation and targeted release rather than merely passively adapting to these processes at the formulation stage.

—Representative ingredients—

Lactase (β-galactosidase)

 

Alpha-galactosidase

 

DPP IV

 

A comprehensive enzyme product system:

NEWGEN boasts a comprehensive enzyme preparation product portfolio with clearly identified enzyme sources and high enzymatic activity. It is suitable for a wide range of application scenarios and dosage forms, including pet powders, tablets, liquids, freeze-dried products, gummies, and chewable candies.

 

Probiotics: Consider formulation compatibility starting from the fermentation stage.

Unlike enzymes, probiotics are more susceptible to the influence of the gastrointestinal environment. Based on its proprietary fermentation system, NEWGEN pays close attention to the state of the microbial cells and their subsequent structural compatibility already during the probiotic production stage, ensuring that the strains exhibit greater consistency and adaptability before entering the CrystoGen™ microcrystal sphere system.

 

Lactobacillus acidophilus HN07: Antioxidant, Anti-inflammatory, and Relief of Colitis Symptoms

 

 

Lactobacillus acidophilus ATCC 4356: Antioxidant—Reduces Metabolism-Related Inflammatory Burden

 

Fermented Lactobacillus mucosae PDD-1: Antioxidant, Liver-Protecting, and Gut Microbiota Structure-Regulating.

Streptococcus thermophilus GYX-8: Antioxidant, Modulates Gut Microbiota, and Enhances Short-Chain Fatty Acid Levels

 

 

Specifically formulated for the digestive tract of dogs and cats.

Compared to humans, the digestive systems of dogs and cats differ significantly in terms of gastric acid strength, feeding rhythms, and the digestion process itself. This means that many ingredients or formulation designs that work well in other species may not be directly suitable for long-term pet nutrition.

In the process of designing pet ingredient and formulation structures at NEWGEN, the actual digestive pathways of dogs and cats have always been the central reference point. It is precisely based on this premise that the CrystoGen™ microcrystal sphere system was designed from the outset with pet applications in mind, ensuring that ingredients, structures, and formulations closely align with the long-term nutritional needs of dogs and cats.

 

 

From raw materials to formula development.

NEWGEN consistently maintains that a formulation design is only truly executable—and not merely theoretical—if the raw materials are factored into the structural and release logic from the very outset of the production stage.

The CrystoGen™ pet microcrystal sphere system is built precisely on this principle: ensuring that the raw materials, formulation, and structure all point toward the same goal from the very beginning—rather than passively coordinating at the application stage.

Based on this raw material and structural foundation, different intestinal nutrition formulations can be systematically developed and designed, validated, and optimized around specific functional objectives. At the same time, the system itself demonstrates excellent adaptability to various dosage forms, supporting a wide range of product formats including powders, granules, tablets, and capsules.

Leveraging its proprietary raw material system and validation platform, NEWGEN can provide partners with a comprehensive support pathway—from raw materials and premixes to finished products—ensuring that formulations not only remain at the conceptual stage but can also be reliably implemented in real-world feeding scenarios.

 

 

 

—About NEWGEN—

About Us

 

Ningbo Xinoa Marine Biotechnology Co., Ltd. is located in Xiangshan County, Ningbo City. Founded in 2013, the company was established by Zhu Hui, an immunology expert who returned to China from the United States. It is a high-tech enterprise that leverages marine biological resources and employs synthetic biology technologies to develop natural, bioactive macromolecular products derived from marine organisms. The company aims to provide innovative solutions for intestinal nutrition and health, thereby boosting the development of nutritional and health services.

 

 

The company is at a globally advanced level in the fields of marine polysaccharides, marine enzyme preparations, and intestinal microbiota ecology. Leveraging its strong capabilities and cutting-edge technologies in the marine biopharmaceutical sector, the company has undertaken numerous national, provincial, and municipal R&D projects, including the National “13th Five-Year Plan” Marine Innovation Development and Demonstration Project, Ningbo’s “2025 Science and Technology Breakthrough” Major Special Project, and Ningbo’s “Challenge-Based Recruitment” Major Special Project.

 

 

The company has obtained numerous quality system certifications, including ISO 22000:2015 Food Management System, ISO 9001:2015 Management System, HACCP Food Management System, Kosher, Halal, and NSF-CGMP. It is a member of several international associations, such as the IPA (International Probiotics Association) and the ETA (Enzyme Technical Association). The company has also received multiple provincial- and city-level awards for technological innovation, including the Third Prize of the Science and Technology Award from the China National Commerce Federation, the Second Prize from the China Invention Association, and the Third Prize of the Ningbo Science and Technology Progress Award. The company places great emphasis on intellectual property protection; as of 2023, it has filed more than 70 patent applications and been granted 36 patents, including 23 authorized invention patents.